mendel
Bring
SUNFLOWER pollen/carpel/seeds
HERMAPHRODITE self-cross; discuss
traits here,
GENOTYPE discussed next.
trait
for ch10: evolving
US population.
Scientific: observe, control variables, statistics/size.
St Thomas's Abbey in Brno Augustinian monastery Czech Republic
genes
Dominates conversation, recedes silent; but some people interm/incomplete: aggressive/passive.
Many genetic diseases RECESSIVE: sickle. Lactase Non-Persistence unexpressed after weaning incomplete?
Nectarine = Mutant Peach? PCR, electrophoresis to detect insertion mutation (Bite-Sci-zed)
Epigenetic inheritance (you are what your grandmother ate) 3:00-7:10 agouti mice and epigenome (NOVA)
Epigenetic inheritance (you are what your grandmother ate) 3:00-7:10 agouti mice and epigenome (NOVA)
Epigenetic therapy (a kinder, gentler chemotherapy: methyl tags to the rescue)
mendelian
TRUE breeding=pure-bred: black hair in Asia!
WHY 1/4 in F2?
See
NEXT punnett.
recessive
bring
WHITE & colored paper: albino absorbs nothing (next topic on giraffe)
But oversimplified: black hair can turn
WHITE - no pigment!
cross
Many diseases
RECESSIVE (lactose, sickle): can predict; but
PUNNETT easier graphic model: random!
punnett
GRAPHICAL model based on knowledge of genes & meiosis
MEIOSIS gametes, giraffe similar to pea:
BROWN pigment;
Note
CAP M for dominant
LOWER m recessive.
Use
PAINT example:
XX x
XY ->boy/girl.
Jnherit from
ANCESTOR evo
phenotype
Bring
WHITE paper:
albino
ABSORBS nothing.
Use M for dominant, m recessive (see Punnett)
punnett_square
Blue eyed baby question based on frequency: can black-haired
TRUE breeding Asians have blond child?
testcross
MARKERS These are
ALLIGATORS ok.
Genetic linkage: dihybrid crosses and gene mapping
incomplete_dominance
Also chlorophylls, hair.
Blonde hair baby -> darker due to hormones; my hair has turned white.
Familial Hypercholesterolaemia:
FH heterozygote has few liver
LDL receptors, cardiovascular disease.
bloodABO
Donated blood only RBC, no plasma.
Blood types and blood compatibility
blood_donation
Type A has anti-B; Type O has both.
XLinked
Color blind gene = R (Receptor?)
SelfQ=0%! EmmaRobertson: father & son color-blind; next son color-blind=50% (mother mustb carrier)
male baldness higher androgen receptor activity on X: castrated produce no androgens; + chromosome 20
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