cell_theory
Fatal
FLAW first cell?
cell
500 nm = .5 µm as shown. Eukaryotes 10-100 µm (egg barely visible)
CELLS total 100M m.
How many cells do you have?
prokaryotic
SAY proteins made by ribosomes.
Note
CIRCULAR genetic
DNA.
READ figure:
genetic info
=DNA inherited from parents: do bacteria have PARENTS?
Nitrobacter nitrite into nitrate in soil.
bilayer
Hydrocarbon
MOLYMOD tail
fluid_mosaic
Revu ch03 nutrition labels: why plant foods no
CHOLESTEROL can fold, fuse.
CARBOHYDRATE added to glycoproteins.
Blood sugar -> insulin(exocytosis from pancreas) for cell uptake.
Liver not insulin-dependent uptake; glucagon glycogen -> glucose.
PLAY insulin first , then Adrenaline ch05: use
MARKERS draw
GDP-GTP,
ADP-ATP-cAMP, liver release glucose from
GLYCOGEN (adrenal glands top of kidneys).
By binding to adrenaline receptors, beta-blockers reduce anxiety symptoms.
Plasma membrane: fluid mosaic model
Pancreas, glucose, and liver: role of insulin receptors in type II diabetes; insulin resistance
Insulin resistance: insulin binds to receptors, but signal cascade fails
Action of epinephrine (adrenaline): role of beta-adrenergic receptors, diffusion, ATP (and GTP), glycogen, glucose
Cholesterol in our blood: VLDL, LDL, and Lp(a)
Cholesterol in our food and in our blood
nucleus
Revu
RIBOSOMES in prokaryotes,
NUCLEAR family=parents+kids
endomembrane
Lysosomes (removed) complete the cycle. Also endosomes.
ER
Carbohydrate: glycogen made in
LIVER and hydrolized in SER; 9 essential amino acids from food.
"within cytoplasm" "little net"; repeat synthesis defined in chap02.
Alcohol abuse -> tolerance to other drugs: more smooth
ER in liver!.
Golgi
transportation/distribution center P Office: to plasma membrane for glycoproteins (carbohydrate chains) or secretion.
mitochondrion
SAY liver
and
MUSCLE cells need energy.
Mitochondrial DNA: tracing human ancestry
Mitochondrial
DNA maternal; no variation;
See 3-parent
BABY in ch05/cloned, ch06/sexual_cycle
chloroplast
Chloroplasts in Elodea: streaming with myosin and actin motor proteins
vacuole
like
BLADDER - osmosis, pigments, make poison
cell_wall
TOILET ch03/cellulose in fruits/veggies - plants
TERMITES eat wood, carpenter ants nest in wood!
cytoskeleton
Micro & intermediate filaments;
Cytoskeleton diversity: microtubules
Cell crawling by actin cytoskeleton: neutrophil on the chase
Cell crawling by actin cytoskeleton: fibroblasts crawling over epithelial cells
Organelle movement along microtubule: kinesin walking, powered by ADP/ATP
PLAY kinesin walking next chap 05:
ADP/ATP power
diffusion
GRADIENT is
like a
BALL or
ORANGE rolling down folder.
Play swf in
FIREFOX browser?
osmosis
Reverse:
reclaim wastewater in CA; rm contaminants; pump thru membrane. Desalination Middle East.
Your kidney at work: osmosis, diffusion, active transport in a nephron
osmotic
TOILET cellulose.
Can u
DRINK lake or sea water?
Fish
PEE.
CELERY NaCL/distilled.
Freshwater fish: need to urinate!
Can we drink seawater?
Reverse osmosis: desalinating seawater in Australia
active_transport
Sodium Potassium Pump: active transport using ATP
endocytosis
MARKERS not
INSIDE yet!
Influenzavirus A more common than B or C,
RNA virus.
Fusion of vesicle with membrane: endocytosis with help of membrane proteins
Amoeba eats two paramecia: by endocytosis
How a flu virus invades your body: by binding to membrane proteins
Endocytosis of LDL Cholesterol: to make new membranes, via vesicles, endosomes, and lysosomes
Liver
LDL receptors rm LDL, move cholesterol to other tissues.
EXOCYTOSIS insulin from pancreas.
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